Biology News

Building a genomic GPS

Biology News - Thu, 2015-03-12 20:06

A new "app" for finding and mapping chromosomal loci using multicolored versions of CRISPR/Cas9, one of the hottest tools in biomedical research today, has been developed by scientists at the University of Massachusetts Medical School. This labeling system, details of which were published in PNAS and first presented at the American Society for Cell Biology/International Federation for Cell Biology annual meeting in Philadelphia in December, could be a key to understanding the spatial and temporal regulation of gene expression by allowing researchers to measure the precise linear distance between two known points on different chromosomes or two locations on the same chromosome in live human cells.

Categories: Biology News, General

NIH researchers develop database on healthy immune system

Biology News - Thu, 2015-03-12 20:06

An extensive database identifying immune traits, such as how immune cell function is regulated at the genetic level in healthy people, is reported by researchers from the National Institutes of Health (NIH) and their collaborators in the journal Cell. While many genetic risk factors have been linked to various diseases, including autoimmune disorders, how a genetic change causes susceptibility to a disease is not always clear. By studying healthy people, researchers from the National Institute of Allergy and Infectious Diseases (NIAID) Vaccine Research Center, part of the NIH, and colleagues from King's College London have created a reference resource for other scientists.

Categories: Biology News, General
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